The Bulldogs are 4-2 overall and 3-1 in the SEC, while the Commodores are 3-3 overall and 0-3 in the league.
Saturday's game in Nashville, Tenn., will kick off at noon and will be televised by CBS.
Monday's practice was the first for the Bulldogs since their 41-26 loss to Missouri last Saturday in Athens.
"It was a pretty good day today," Georgia coach Mark Richt said. "We definitely got better. It was a good start to the week, and we'll need to keep that going. I thought the guys showed a lot of focus and energy today.”
"It can be pretty hard to come out after a loss, but we know we have to put it behind us," defensive end Leonard Floyd said. "We don't have any time to dwell on Missouri. We have to put all our attention on Vanderbilt now. They have a good team and we will have to be ready."
Richt said the captains for Saturday's game will be center David Andrews and quarterback Aaron Murray on offense, end Garrison Smith on defense, and fullback Corey Campbell on special teams.
Georgia owns a 53-18-2 edge in the series with Vanderbilt. The Bulldogs have won the last six games in the series and 17 of the past 18. Georgia is 24-7-1 all-time at Vanderbilt Stadium, including 10 straight.
Murray has two more SEC career records that are within reach Saturday. Currently, he ranks second in total offense and touchdown passes. He has 12,203 yards of total offense, trailing Tim Tebow (Florida 2006-09) by just 29 yards. This season, Murray ranks second in total offense in the SEC at 317.0 yards per game. The SEC record for career touchdown passes is 114 by Danny Wuerffel (Florida 1993-96). Murray has 112 TD passes entering the Vanderbilt game, including an SEC-best 17 this year. Murray already is SEC's all-time leader in passing yardage with 11,915 passing yards.